I think one of the most surprising bit of information I learned is that when thinking about personal genomics and its relation to prediction, the main motivation behind the project is an alternate way to predict the fate of future generations besides simply choosing whether or not to have kids. I also thought an interesting bit of information was advanced imaging and its role in the advancement of genomics research. This imaging is a method to view and reconstruct molecules (such as DNA, chromosomes, cells, etc.) which is fundamental in methods of editing DNA and changing a patient's fate, like CRISPR. These methods of reading, though computationally intense, allows researchers to read molecules and represent them in different dimensions to create new gene therapies to cure ailments like HIV and blindness.
If I conducted the interview, I would like to ask his thoughts on the intersection of computational sciences and the personal genome project. I am particularly interested in encryption schemes and the privacy of participants' data, and his predictions on the impact of various technological advancements on the field and the project. I am interested in this since a few of my computer science classes have touched on genomics being a large application of my field, and I would like to hear an explanation from this from someone in this area of research.
Loved your take, Miah! I think the discussion of visualization was particularly interesting, especially regarding the potential applications to CRISPR and new gene therapies. The interview reveals a significant concern for the future of prediction in genomic research. Hearing about your question on best practices for preserving sensitive user data in large aggregation projects is super important in the age of big data and the potential ethical concerns of information leaking that can occur. I wonder to what extent this sensitive data will be protected in the future. Thanks Miah!
Please ask in class to hear more about the intersection of computational approaches and genomics! I have been working on that a bit these days