I liked that Professor Firestein framed scientific progression in terms of ignorance as well as terms of success. While it is tempting to believe that the scientific lexicon as we understand right now it is perfect, looking at the history of medical science suggests that we are probably doing some things wrong with the way that we view and treat certain ailments. We still have no idea why some people get type 2 diabetes and others don't despite similar risk profiles. We also don't really know why some people have what is sometimes described in the medical community as "poor protoplasm" or inexplicable frailty or sickliness. I think that the point to acknowledge the ignorance and to understand that sometimes ignorance can lead to brilliant conclusions- such as neuroscience having its foundation in the pseudoscience of phrenology. We are still learning about how the world works, and part of the learning process is recognizing that we might come to some wrong conclusions or observe inexplicable phenomena since we don't fully understand everything yet.