I think the most interesting bit of information I learned is that, in the search for extraterrestrial communication, scientists look for communication in a really broad range of frequency. This is where a good portion of the uncertainty in this field comes from and, according to Jill Tarter, has been the cause of false positives in detecting intelligent beings outside of Earth. This wide band of frequencies being used in order to anticipate extraterrestrials reaching out, while being a feat in computation, requires those detecting the frequencies to filter between what is normal communication and what is abnormal.
If I conducted the interview, I would ask what the methods of "calculating" uncertainty in space exploration are, if there are any. In particular, I am interested in how certain we are of there being other intelligent civilizations, what the probability is that these civilizations having motivations to contact us, and how we could gauge if these civilizations are hostile.