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    William Foulkes
    Dash  ·  
    Mar 31, 2021

    Question for George Church (https://www.labxchange.org/library/pathway/lx-pathway:0b417a9e-6227-44a8-a887-dbfdf44e37e3/items/lx-pb:0b417a9e-

    in Thoughts from Learners

    My favorite question that Professor Goodman asked is “what are you actually doing?” in terms of using CRISPR to edit someone’s genes. I found the answer pretty satisfying, even if I don’t quite understand what it would look like physically to insert or remove genes from a person. You also discussed the level of knowledge you feel people need to have before receiving information about their predispositions for certain diseases that they might receive if they take part in mapping their genomes. For example, they need to know what it means to have a 90% chance of developing breast cancer. While undergoing gene therapy in a clinical trial, what kinds of things do people absolutely need to know before they take part in the trial? I assume they don’t need to know what the doctors physically do, but I imagine there are a number of uncertainties that doctors would need to express to their patients in clear terms.

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