One question I would ask Avi Loeb is when he thinks humans and current life will no longer exist. He stated that it is likely that we will die out and a more durable creature such as robots or aliens that will take our place. I wonder how far out in the future he thinks this will happen.
https://www.labxchange.org/library/pathway/lx-pathway:34dd3b2c-3aec-460a-817f-da4af2ed1577/items/lx-pb:34dd3b2c-3aec-460a-817f-da4af2ed1577:lx_simulation:1a066234?source=%2Flibrary%2Fclusters%2Flx-cluster%3AModernPrediction
That also had me wondering. Neuralink already managed to get a monkey to play pong through a chip in its brain, so maybe not so far in the future...